Case Study: Fluid Bed Drying of Antibiotic and Isatis Root Granules for the Hong Kong Market

1. Market Background

Pharmaceutical manufacturers in Hong Kong face strict quality and consistency requirements, especially in the production of:

• Antibiotic granules
   
• Traditional Chinese medicine granules (e.g., Isatis root granules)
  
   

Common challenges include:

• Moisture variability after wet granulation
  
   
• Particle size inconsistency
  
   
• Agglomeration during storage
   

2. Customer & Application Scenario
 

Client produces wet granulated materials through a process of:


Wet granulation → Drying → Screening → Packaging

 

Key material characteristics:

• High initial moisture content
   
• Controlled particle size required
   
• Temperature-sensitive active ingredients

3. Solution: Vibrating Fluid Bed Dryer

A ZLG vibrating fluidized bed dryer was implemented.

Key configuration:

• Contact material: 316L stainless steel
   
• Vibration frequency: ~960 r/min (adjustable)
   
• Inlet air temperature: 70–140°C
   
• Continuous operation design
  
   

4. Performance in Operation

• Stable moisture control after drying
   
• Consistent particle integrity without breakage
   
• Reduced agglomeration during storage
   
• Stable operation under continuous production
   

5. Key Technical Support

• Adjustable vibration ensures uniform fluidization
   
• Controlled temperature range supports sensitive materials
   
• Uniform air distribution improves drying consistency
  
   

6. Conclusion

For pharmaceutical granule drying in Hong Kong, vibrating fluid bed dryers provide a controlled and stable solution by combining:
 

• Adjustable process parameters
   
• GMP-compatible materials
   
• Continuous drying capability
   
•  

This enables consistent product quality without relying on empirical adjustments

.